Nanoparticles based sensors for rapid detection of foodborne pathogens
Keywords:
nano-sensor, magnetic nano-particle, food pathogens, nuclear magnetic resonanceAbstract
Rapid detection of foodborne pathogens is a key step in the control of food related diseases. Conventional methods for the detection of food pathogens, although typically sensitive, often require multiple time-consuming steps such as extraction, isolation, enrichment, counting, etc., prior to measurement, resulting in testing times which can be days. There is a need to develop rapid and sensitive detection methods. This review is intended to provide food scientists and engineers an overview of current rapid detection methods, a close look at the nanoparticles especially magnetic nanoparticle-antibody conjugates based methods, and identification of knowledge gaps and future research needs.References
[1] Panchal R G, Halverson K M, Ribot W, Lane D, Kenny T, Abshire T G, et al. Purified Bacillus anthracis lethal toxin complex formed in vitro and during infection exhibits functional and biological activity. J Biol Chem, 2005; 280(11): 10834-10839.
[2] Mirkin C A, Letsinger R L, Mucic R C, Storhoff J J. A DNA-based method for rationally assembling nanoparticles into macroscopic materials. Nature, 1996; 382(6592): 607- 609.
[3] Kayal S, Charbit A. Listeriolysin O. A key protein of Listeria monocytogenes with multiple functions. FEMS Microbiol Rev, 2006; 30(4): 514-529.
[4] Medina M B. Development of a fluorescent latex microparticle immunoassay for the detection of staphylococcal enterotoxin B (SEB). J Agric Food Chem, 2006; 54(14): 4937-4942.
[5] Chen S, Carroll D L. Synthesis and characterization of truncated triangular silver nanoplates. Nano Lett, 2002; 2: 1003-1007.
[6] Swaminathan B, Feng P. Rapid detection of food-borne pathogenic bacteria. Annual Review of Microbiology, 1994; 48: 401-426.
[7] Feng P. Rapid methods for detecting foodborne pathogens. In: FDA, editor. Bacteriological Analytical Manual Online, 2001.
[8] Jain K K. Nanotechnology in clinical laboratory diagnostics. Clin Chim Acta, 2005; 358(1-2): 37-54.
[9] Saxena S K, O'Brien A D, Ackerman E J. Shiga toxin, Shiga-like toxin II variant, and ricin are all single-site RNA N-glycosidases of 28 S RNA when microinjected into Xenopus oocytes. J Biol Chem, 1989; 264(1): 596-601.
[10] Salyers A A, Whitt D D. Bacterial Pathogenesis: A Molecular Approach. 2nd ed. Washington, D.C: ASM Press; 2002.
[11] Banada P P, Bhunia A K. Antibodies and immunoassays for detection of bacterial pathogens. Principles of Bacterial Detection: Biosensors, Recognition Receptors and Microsystems, 2008; pp. 567-602.
[12] Kaittanis C, Santra S, Perez J M. Emerging nanotechnology-based strategies for the identification of microbial pathogenesis. Adv Drug Deliv Rev, 2009..
[13] O'Farrell N, Houlton A, Horrocks B R. Silicon nanoparticles: applications in cell biology and medicine. Int J Nanomedicine, 2006; 1(4): 451-472.
[14] Salata O. Applications of nanoparticles in biology and medicine. J Nanobiotechnology, 2004; 2(1): 3.
[15] Elghanian R, Storhoff J J, Mucic R C, Letsinger R L, Mirkin C A. Selective colorimetric detection of polynucleotides based on the distance-dependent optical properties of gold nanoparticles. Science, 1997; 277(5329): 1078-1081.
[16] Qin D, He X, Wang K, Tan W. Using fluorescent nanoparticles and SYBR Green I based two-color flow cytometry to determine Mycobacterium tuberculosis avoiding false positives. Biosens Bioelectron, 2008; 24(4): 626-631.
[17] Edgar R, McKinstry M, Hwang J, Oppenheim A B, Fekete R A, Giulian G, et al. High-sensitivity bacterial detection using biotin-tagged phage and quantum-dot nanocomplexes. Proc Natl Acad Sci U S A, 2006; 103(13): 4841-4845.
[18] Rosi N L, Mirkin C A. Nanostructures in biodiagnostics. Chem Rev, 2005; 105(4): 1547-1562.
[19] Weinstein J S, Varallyay C G, Dosa E, Gahramanov S, Hamilton B, Rooney W D, et al. Superparamagnetic iron oxide nanoparticles: diagnostic magnetic resonance imaging and potential therapeutic applications in neurooncology and central nervous system inflammatory pathologies, a review. J Cereb Blood Flow Metab, 2010; 30(1): 15-35.
[20] Jain T K, Richey J, Strand M, Leslie-Pelecky D L, Flask C A, Labhasetwar V. Magnetic nanoparticles with dual functional properties: drug delivery and magnetic resonance imaging. Biomaterials, 2008; 29(29): 4012-4021.
[21] Sun C, Lee J S, Zhang M. Magnetic nanoparticles in MR imaging and drug delivery. Adv Drug Deliv Rev, 2008; 60(11): 1252-1265.
[22] Sosnovik D E, Nahrendorf M, Weissleder R. Magnetic nanoparticles for MR imaging: agents, techniques and cardiovascular applications. Basic Res Cardiol, 2008; 103(2): 122-130.
[23] Yang J, Gunn J, Dave S R, Zhang M, Wang Y A, Gao X. Ultrasensitive detection and molecular imaging with magnetic nanoparticles. Analyst, 2008; 133(2): 154-160.
[24] Cao M, Li Z, Wang J, Ge W, Yue T, Li R, et al. Food related applications of magnetic iron oxide nanoparticles: Enzyme immobilization, Protein purification, and food analysis. Trends in Food Science & Technology, 2012; 27(1): 47-56.
[25] Chiang C L, Sung C S, Wu T F, Chen C Y, Hsu C Y. Application of superparamagnetic nanoparticles in purification of plasmid DNA from bacterial cells. J Chromatogr B Analyt Technol Biomed Life Sci, 2005; 822(1-2): 54-60.
[26] Bao J, Chen W, Liu T, Zhu Y, Jin P, Wang L, et al. Bifunctional Au-Fe3O4 nanoparticles for protein separation. ACS Nano, 2007; 1(4): 293-298.
[27] Gu H, Xu K, Xu C, Xu B. Biofunctional magnetic nanoparticles for protein separation and pathogen detection. Chem Commun (Camb), 2006; (9): 941-9.
[28] Varshney M, Yang L, Su X L, Li Y. Magnetic nanoparticle-antibody conjugates for the separation of Escherichia coli O157:H7 in ground beef. J Food Prot, 2005; 68(9): 1804-1811.
[29] Hua Y, Liangwei Q, Wimbrow A N, Xiuping J, Yaping S. Rapid detection of Listeria monocytogenes by nanoparticle-based immunomagnetic separation and real-time PCR. International Journal of Food Microbiology, 2007; 118(2): 132-138.
[30] Perez J M, Wilhelm E J, Sucholeiki I. The use of power ultrasound coupled with magnetic separation for the solid phase synthesis of compound libraries. Bioorg Med Chem Lett, 2000; 10(2): 171-174.
[31] Gupta A K, Gupta M. Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications. Biomaterials, 2005; 26(18): 3995-4021.
[32] Duan H L, Shen Z Q, Wang X W, Chao F H, Li J W. Preparation of immunomagnetic iron-dextran nanoparticles and application in rapid isolation of E.coli O157:H7 from foods. World J Gastroenterol, 2005; 11(24): 3660-3664.
[33] Josephson L, Tung C H, Moore A, Weissleder R. High-Efficiency Intracellular Magnetic Labeling with Novel Superparamagnetic-Tat Peptide Conjugates. Bioconjugate Chemistry, 1999; 10(2): 186-191.
[34] Koh I, Hong R, Weissleder R, Josephson L. Nanoparticle-target interactions parallel antibody-protein interactions. Anal Chem, 2009; 81(9): 3618-3622.
[35] Perez J M, Josephson L, Weissleder R. Use of magnetic nanoparticles as nanosensors to probe for molecular interactions. ChemBioChem, 2004; 5(3): 261-264.
[36] Nath S, Kaittanis C, Ramachandran V, Dalal N S, Perez J M. Synthesis, Magnetic Characterization, and Sensing Applications of Novel Dextran-Coated Iron Oxide Nanorods. Chemistry of Materials, 2009; 21(8): 1761-1767.
[37] Kaittanis C, Naser S A, Perez J M. One-step, nanoparticle-mediated bacterial detection with magnetic relaxation. Nano Lett, 2007; 7(2): 380-383.
[38] Lee H, Sun E, Ham D, Weissleder R. Chip-NMR biosensor for detection and molecular analysis of cells. Nat Med. 2008; 14(8): 869-874.
[39] Perez J M, Josephson L, O'Loughlin T, Hogemann D, Weissleder R. Magnetic relaxation switches capable of sensing molecular interactions. Nat Biotechnol, 2002; 20(8): 816-820.
[40] Perez J M, Simeone F J, Saeki Y, Josephson L, Weissleder R. Viral-induced self-assembly of magnetic nanoparticles allows the detection of viral particles in biological media. J Am Chem Soc, 2003; 125(34): 10192-10193.
[41] Kaittanis C, Nath S, Perez J M. Rapid nanoparticle- mediated monitoring of bacterial metabolic activity and assessment of antimicrobial susceptibility in blood with magnetic relaxation. PLoS One, 2008; 3(9): e3253.
[42] Mao X, Yang L, Su X L, Li Y. A nanoparticle amplification based quartz crystal microbalance DNA sensor for detection of Escherichia coli O157:H7. Biosensors and Bioelectronics, 2006; 21(7): 1178-1185.
[43] Liu F, Li Y, Su X L, Slavik M, Ying Y, Wang J. QCM immunosensor with nanoparticle amplification for detection of Escherichia coli O157:H7. Sensing and Instrumentation for Food Quality and Safety, 2007; 1(4): 161-168.
[44] Lowery T J, Palazzolo R, Wong S M, Prado P J, Taktak S. Single-coil, multisample, proton relaxation method for magnetic relaxation switch assays. Analytical chemistry, 2008; 80(4): 1118-1123.
[45] Fornara A, Johansson P, Petersson K, Gustafsson S, Qin J, Olsson E, et al. Tailored magnetic nanoparticles for direct and sensitive detection of biomolecules in biological samples. Nano Lett, 2008; 8(10): 3423-3428.
[46] Kaittanis C, Santra S, Perez J M. Role of nanoparticle valency in the nondestructive magnetic-relaxation-mediated detection and magnetic isolation of cells in complex media. J Am Chem Soc. 2009; 131(35): 12780-12791.
[47] Perez J M, O'Loughin T, Simeone F J, Weissleder R, Josephson L. DNA-based magnetic nanoparticle assembly acts as a magnetic relaxation nanoswitch allowing screening of DNA-cleaving agents. J Am Chem Soc. 2002; 124(12): 2856-2857.
[48] Farahi R, Passian A, Tetard L, Thundat T. Critical issues in sensor science to aid food and water safety. ACS Nano, 2012; 6(6): 4548-4556.
[49] Respaud M, Broto J M, Rakoto H, Fert A R, Thomas L, Barbara B, et al. Surface effects on the magnetic properties of ultrafine cobalt particles. Physical Review B, 1998; 57: 2925.
[50] B?dker F, M?rup S, Linderoth S. Surface effects in metallic iron nanoparticles. Physical Review Letters, 1994; 72: 282.
[51] Paulus P M, B?nnemann H, van der Kraan A M, Luis F, Sinzig J, de Jongh L J. Magnetic properties of nanosized transition metal colloids: the influence of noble metal coating. The European Physical Journal D - Atomic, Molecular, Optical and Plasma Physics, 1999; 9(1): 501-504.
[52] Kaittanis C, Santra S, Perez J M. Role of Nanoparticle Valency in the Nondestructive Magnetic-Relaxation- Mediated Detection and Magnetic Isolation of Cells in Complex Media. Journal of the American Chemical Society, 2009; 131(35): 12780-12791.
[53] Ruan R R, Chen P L. Water in foods and biological materials. Lancaster, Pa.: Technomic Pub. Co.; 1998.
[54] Schoenfelder W, Gl?ser H-R, Mitreiter I, Stallmach F. Two-dimensional NMR relaxometry study of pore space characteristics of carbonate rocks from a Permian aquifer. Journal of Applied Geophysics, 2008; 65(1): 21-29.
[55] Marigheto N, Moates G, Furfaro M, Waldron K, Hills B. Characterisation of Ripening and Pressure-Induced Changes in Tomato Pericarp Using NMR Relaxometry. Applied Magnetic Resonance, 2009; 36(1): 35-47.
[56] Bie C, Ruan R, Chen P, editors. NMR study of the states of water in dough. ASAE/CSAE-SCGR Annual International Meeting; 1999 18-21 July, 1999; Toronto, Ontario, Canada: American Society of Agricultural Engineers (ASAE), St Joseph, USA.
[57] Chen P L, Long Z, Ruan R, Labuza T P. Nuclear Magnetic resonance studies of water mobility in bread during storage. Lebensmittel Wissenschaft & Technologie, 1997; 30(2): 178-183.
[58] Chulkyoon M, Jinning Q, Chen P, Ruan R. NMR relaxometry of water in set yogurt during fermentation. Food Science & Biotechnology, 2008; 17(5): 895-898.
[59] Chung M, Ruan R, Chen P, editors. Study of caking of powdered foods using nuclear magnetic resonance (NMR). ASAE/CSAE-SCGR Annual International Meeting; 1999 18-21 July, 1999; Toronto, Ontario, Canada: American Society of Agricultural Engineers (ASAE), St Joseph, USA.
[60] Lin X, Ruan R, Chen P, Chung M, Ye X, Yang T, et al. NMR state diagram concept. Journal of Food Science, 2006; 71(9): R136-R145.
[61] Ruan R R, Chen P L, Roles, Editors. Water in foods and biological materials: a nuclear magnetic resonance approach. Technomic Publishing Co., Inc., Lancaster-Basel, 1998; 298(Other): 298.
[62] Hogemann D, Ntziachristos V, Josephson L, Weissleder R. High throughput magnetic resonance imaging for evaluating targeted nanoparticle probes. Bioconjugate Chemistry, 2002; 13(1): 116-121.
[2] Mirkin C A, Letsinger R L, Mucic R C, Storhoff J J. A DNA-based method for rationally assembling nanoparticles into macroscopic materials. Nature, 1996; 382(6592): 607- 609.
[3] Kayal S, Charbit A. Listeriolysin O. A key protein of Listeria monocytogenes with multiple functions. FEMS Microbiol Rev, 2006; 30(4): 514-529.
[4] Medina M B. Development of a fluorescent latex microparticle immunoassay for the detection of staphylococcal enterotoxin B (SEB). J Agric Food Chem, 2006; 54(14): 4937-4942.
[5] Chen S, Carroll D L. Synthesis and characterization of truncated triangular silver nanoplates. Nano Lett, 2002; 2: 1003-1007.
[6] Swaminathan B, Feng P. Rapid detection of food-borne pathogenic bacteria. Annual Review of Microbiology, 1994; 48: 401-426.
[7] Feng P. Rapid methods for detecting foodborne pathogens. In: FDA, editor. Bacteriological Analytical Manual Online, 2001.
[8] Jain K K. Nanotechnology in clinical laboratory diagnostics. Clin Chim Acta, 2005; 358(1-2): 37-54.
[9] Saxena S K, O'Brien A D, Ackerman E J. Shiga toxin, Shiga-like toxin II variant, and ricin are all single-site RNA N-glycosidases of 28 S RNA when microinjected into Xenopus oocytes. J Biol Chem, 1989; 264(1): 596-601.
[10] Salyers A A, Whitt D D. Bacterial Pathogenesis: A Molecular Approach. 2nd ed. Washington, D.C: ASM Press; 2002.
[11] Banada P P, Bhunia A K. Antibodies and immunoassays for detection of bacterial pathogens. Principles of Bacterial Detection: Biosensors, Recognition Receptors and Microsystems, 2008; pp. 567-602.
[12] Kaittanis C, Santra S, Perez J M. Emerging nanotechnology-based strategies for the identification of microbial pathogenesis. Adv Drug Deliv Rev, 2009..
[13] O'Farrell N, Houlton A, Horrocks B R. Silicon nanoparticles: applications in cell biology and medicine. Int J Nanomedicine, 2006; 1(4): 451-472.
[14] Salata O. Applications of nanoparticles in biology and medicine. J Nanobiotechnology, 2004; 2(1): 3.
[15] Elghanian R, Storhoff J J, Mucic R C, Letsinger R L, Mirkin C A. Selective colorimetric detection of polynucleotides based on the distance-dependent optical properties of gold nanoparticles. Science, 1997; 277(5329): 1078-1081.
[16] Qin D, He X, Wang K, Tan W. Using fluorescent nanoparticles and SYBR Green I based two-color flow cytometry to determine Mycobacterium tuberculosis avoiding false positives. Biosens Bioelectron, 2008; 24(4): 626-631.
[17] Edgar R, McKinstry M, Hwang J, Oppenheim A B, Fekete R A, Giulian G, et al. High-sensitivity bacterial detection using biotin-tagged phage and quantum-dot nanocomplexes. Proc Natl Acad Sci U S A, 2006; 103(13): 4841-4845.
[18] Rosi N L, Mirkin C A. Nanostructures in biodiagnostics. Chem Rev, 2005; 105(4): 1547-1562.
[19] Weinstein J S, Varallyay C G, Dosa E, Gahramanov S, Hamilton B, Rooney W D, et al. Superparamagnetic iron oxide nanoparticles: diagnostic magnetic resonance imaging and potential therapeutic applications in neurooncology and central nervous system inflammatory pathologies, a review. J Cereb Blood Flow Metab, 2010; 30(1): 15-35.
[20] Jain T K, Richey J, Strand M, Leslie-Pelecky D L, Flask C A, Labhasetwar V. Magnetic nanoparticles with dual functional properties: drug delivery and magnetic resonance imaging. Biomaterials, 2008; 29(29): 4012-4021.
[21] Sun C, Lee J S, Zhang M. Magnetic nanoparticles in MR imaging and drug delivery. Adv Drug Deliv Rev, 2008; 60(11): 1252-1265.
[22] Sosnovik D E, Nahrendorf M, Weissleder R. Magnetic nanoparticles for MR imaging: agents, techniques and cardiovascular applications. Basic Res Cardiol, 2008; 103(2): 122-130.
[23] Yang J, Gunn J, Dave S R, Zhang M, Wang Y A, Gao X. Ultrasensitive detection and molecular imaging with magnetic nanoparticles. Analyst, 2008; 133(2): 154-160.
[24] Cao M, Li Z, Wang J, Ge W, Yue T, Li R, et al. Food related applications of magnetic iron oxide nanoparticles: Enzyme immobilization, Protein purification, and food analysis. Trends in Food Science & Technology, 2012; 27(1): 47-56.
[25] Chiang C L, Sung C S, Wu T F, Chen C Y, Hsu C Y. Application of superparamagnetic nanoparticles in purification of plasmid DNA from bacterial cells. J Chromatogr B Analyt Technol Biomed Life Sci, 2005; 822(1-2): 54-60.
[26] Bao J, Chen W, Liu T, Zhu Y, Jin P, Wang L, et al. Bifunctional Au-Fe3O4 nanoparticles for protein separation. ACS Nano, 2007; 1(4): 293-298.
[27] Gu H, Xu K, Xu C, Xu B. Biofunctional magnetic nanoparticles for protein separation and pathogen detection. Chem Commun (Camb), 2006; (9): 941-9.
[28] Varshney M, Yang L, Su X L, Li Y. Magnetic nanoparticle-antibody conjugates for the separation of Escherichia coli O157:H7 in ground beef. J Food Prot, 2005; 68(9): 1804-1811.
[29] Hua Y, Liangwei Q, Wimbrow A N, Xiuping J, Yaping S. Rapid detection of Listeria monocytogenes by nanoparticle-based immunomagnetic separation and real-time PCR. International Journal of Food Microbiology, 2007; 118(2): 132-138.
[30] Perez J M, Wilhelm E J, Sucholeiki I. The use of power ultrasound coupled with magnetic separation for the solid phase synthesis of compound libraries. Bioorg Med Chem Lett, 2000; 10(2): 171-174.
[31] Gupta A K, Gupta M. Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications. Biomaterials, 2005; 26(18): 3995-4021.
[32] Duan H L, Shen Z Q, Wang X W, Chao F H, Li J W. Preparation of immunomagnetic iron-dextran nanoparticles and application in rapid isolation of E.coli O157:H7 from foods. World J Gastroenterol, 2005; 11(24): 3660-3664.
[33] Josephson L, Tung C H, Moore A, Weissleder R. High-Efficiency Intracellular Magnetic Labeling with Novel Superparamagnetic-Tat Peptide Conjugates. Bioconjugate Chemistry, 1999; 10(2): 186-191.
[34] Koh I, Hong R, Weissleder R, Josephson L. Nanoparticle-target interactions parallel antibody-protein interactions. Anal Chem, 2009; 81(9): 3618-3622.
[35] Perez J M, Josephson L, Weissleder R. Use of magnetic nanoparticles as nanosensors to probe for molecular interactions. ChemBioChem, 2004; 5(3): 261-264.
[36] Nath S, Kaittanis C, Ramachandran V, Dalal N S, Perez J M. Synthesis, Magnetic Characterization, and Sensing Applications of Novel Dextran-Coated Iron Oxide Nanorods. Chemistry of Materials, 2009; 21(8): 1761-1767.
[37] Kaittanis C, Naser S A, Perez J M. One-step, nanoparticle-mediated bacterial detection with magnetic relaxation. Nano Lett, 2007; 7(2): 380-383.
[38] Lee H, Sun E, Ham D, Weissleder R. Chip-NMR biosensor for detection and molecular analysis of cells. Nat Med. 2008; 14(8): 869-874.
[39] Perez J M, Josephson L, O'Loughlin T, Hogemann D, Weissleder R. Magnetic relaxation switches capable of sensing molecular interactions. Nat Biotechnol, 2002; 20(8): 816-820.
[40] Perez J M, Simeone F J, Saeki Y, Josephson L, Weissleder R. Viral-induced self-assembly of magnetic nanoparticles allows the detection of viral particles in biological media. J Am Chem Soc, 2003; 125(34): 10192-10193.
[41] Kaittanis C, Nath S, Perez J M. Rapid nanoparticle- mediated monitoring of bacterial metabolic activity and assessment of antimicrobial susceptibility in blood with magnetic relaxation. PLoS One, 2008; 3(9): e3253.
[42] Mao X, Yang L, Su X L, Li Y. A nanoparticle amplification based quartz crystal microbalance DNA sensor for detection of Escherichia coli O157:H7. Biosensors and Bioelectronics, 2006; 21(7): 1178-1185.
[43] Liu F, Li Y, Su X L, Slavik M, Ying Y, Wang J. QCM immunosensor with nanoparticle amplification for detection of Escherichia coli O157:H7. Sensing and Instrumentation for Food Quality and Safety, 2007; 1(4): 161-168.
[44] Lowery T J, Palazzolo R, Wong S M, Prado P J, Taktak S. Single-coil, multisample, proton relaxation method for magnetic relaxation switch assays. Analytical chemistry, 2008; 80(4): 1118-1123.
[45] Fornara A, Johansson P, Petersson K, Gustafsson S, Qin J, Olsson E, et al. Tailored magnetic nanoparticles for direct and sensitive detection of biomolecules in biological samples. Nano Lett, 2008; 8(10): 3423-3428.
[46] Kaittanis C, Santra S, Perez J M. Role of nanoparticle valency in the nondestructive magnetic-relaxation-mediated detection and magnetic isolation of cells in complex media. J Am Chem Soc. 2009; 131(35): 12780-12791.
[47] Perez J M, O'Loughin T, Simeone F J, Weissleder R, Josephson L. DNA-based magnetic nanoparticle assembly acts as a magnetic relaxation nanoswitch allowing screening of DNA-cleaving agents. J Am Chem Soc. 2002; 124(12): 2856-2857.
[48] Farahi R, Passian A, Tetard L, Thundat T. Critical issues in sensor science to aid food and water safety. ACS Nano, 2012; 6(6): 4548-4556.
[49] Respaud M, Broto J M, Rakoto H, Fert A R, Thomas L, Barbara B, et al. Surface effects on the magnetic properties of ultrafine cobalt particles. Physical Review B, 1998; 57: 2925.
[50] B?dker F, M?rup S, Linderoth S. Surface effects in metallic iron nanoparticles. Physical Review Letters, 1994; 72: 282.
[51] Paulus P M, B?nnemann H, van der Kraan A M, Luis F, Sinzig J, de Jongh L J. Magnetic properties of nanosized transition metal colloids: the influence of noble metal coating. The European Physical Journal D - Atomic, Molecular, Optical and Plasma Physics, 1999; 9(1): 501-504.
[52] Kaittanis C, Santra S, Perez J M. Role of Nanoparticle Valency in the Nondestructive Magnetic-Relaxation- Mediated Detection and Magnetic Isolation of Cells in Complex Media. Journal of the American Chemical Society, 2009; 131(35): 12780-12791.
[53] Ruan R R, Chen P L. Water in foods and biological materials. Lancaster, Pa.: Technomic Pub. Co.; 1998.
[54] Schoenfelder W, Gl?ser H-R, Mitreiter I, Stallmach F. Two-dimensional NMR relaxometry study of pore space characteristics of carbonate rocks from a Permian aquifer. Journal of Applied Geophysics, 2008; 65(1): 21-29.
[55] Marigheto N, Moates G, Furfaro M, Waldron K, Hills B. Characterisation of Ripening and Pressure-Induced Changes in Tomato Pericarp Using NMR Relaxometry. Applied Magnetic Resonance, 2009; 36(1): 35-47.
[56] Bie C, Ruan R, Chen P, editors. NMR study of the states of water in dough. ASAE/CSAE-SCGR Annual International Meeting; 1999 18-21 July, 1999; Toronto, Ontario, Canada: American Society of Agricultural Engineers (ASAE), St Joseph, USA.
[57] Chen P L, Long Z, Ruan R, Labuza T P. Nuclear Magnetic resonance studies of water mobility in bread during storage. Lebensmittel Wissenschaft & Technologie, 1997; 30(2): 178-183.
[58] Chulkyoon M, Jinning Q, Chen P, Ruan R. NMR relaxometry of water in set yogurt during fermentation. Food Science & Biotechnology, 2008; 17(5): 895-898.
[59] Chung M, Ruan R, Chen P, editors. Study of caking of powdered foods using nuclear magnetic resonance (NMR). ASAE/CSAE-SCGR Annual International Meeting; 1999 18-21 July, 1999; Toronto, Ontario, Canada: American Society of Agricultural Engineers (ASAE), St Joseph, USA.
[60] Lin X, Ruan R, Chen P, Chung M, Ye X, Yang T, et al. NMR state diagram concept. Journal of Food Science, 2006; 71(9): R136-R145.
[61] Ruan R R, Chen P L, Roles, Editors. Water in foods and biological materials: a nuclear magnetic resonance approach. Technomic Publishing Co., Inc., Lancaster-Basel, 1998; 298(Other): 298.
[62] Hogemann D, Ntziachristos V, Josephson L, Weissleder R. High throughput magnetic resonance imaging for evaluating targeted nanoparticle probes. Bioconjugate Chemistry, 2002; 13(1): 116-121.
Published
2013-03-19
How to Cite
Chen, P., Li, Y., Cui, T., & Ruan, R. (2013). Nanoparticles based sensors for rapid detection of foodborne pathogens. International Journal of Agricultural and Biological Engineering, 6(1), 28–35. Retrieved from https://ijabe.migration.pkpps03.publicknowledgeproject.org/index.php/ijabe/article/view/734
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